Obesity increases long-term COVID risk, study finds

June 8, 2021 – obesity – a major risk factor in the development of severe infection or death from COVID-19 infection – also significantly increases the risk of developing long-term complications from the disease, a syndrome often referred to as long-distance COVID-19, a new According to the study.

“To our knowledge, this present study reports for the first time that patients with moderate to severe obesity Study lead author Ali Aminian, MD, director of the Cleveland Clinic’s Bariatric and Metabolic Institute, said in a press statement, those beyond the acute phase are at greater risk of developing long-term complications of COVID-19.

The study included 2,839 patients who tested positive for COVID-19 at the Cleveland Clinic Health System between March and July 2020, did not require ICU admission and survived the early stages of COVID-19.

Doctors looked for three indicators of potential long-term complications of COVID-19 — hospital admissions, death and the need for diagnostic medical tests — that are viral first positive for COVID-19. Occurred 30 days or more after the test.

In the 10 months following their initial COVID-19 infection, 44% of patients required hospitalization and 1% had died.

The need for clinical trials after infection was 25% higher in those with moderate obesity (BMI of 35–39.9) and 39% higher in those with severe. obesity (BMI >40), compared to those with a BMI of 18.5–24.9.

Specifically, obese people were more likely to need clinical tests for heart, lung and Kidney; for gastrointestinal or hormonal symptoms; or blood disorder; and for mental health Problems after COVID-19 infection.

However, obesity was not associated with a higher risk of death during the follow-up period.

The findings suggest that the effects of obesity extend beyond worsening infection and affect long-term symptoms.

“The observations of this study could possibly be explained by underlying mechanisms at work in obese patients, such as hyperinflammation, immune dysfunction and comorbidities,” said senior author Bartolome Barguera, MD, PhD, in a Cleveland Clinic press statement. .

While a wide range of mild long-term effects after COVID-19 infection, including psychotic symptoms, fatigueWhile , brain fog, muscle weakness, and sleeping difficulties have been reported, the current study does not include information on those symptoms.

However, even the finding that 44% of patients required hospital admission after COVID-19 — regardless of weight status — is a matter of concern, the authors said.

“These findings suggest a profound magnitude of the public health impact [long-haul COVID-19] In the setting of worldwide transition,” he wrote.

Study is published in the journal Diabetes, obesity and metabolism.

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