Why vaccinated people are having ‘breakthrough’ infections

Whether a vaccinated person is ever infected depends on how high the antibodies are after vaccination, how potent those antibodies are, and whether the person’s blood levels of antibodies have decreased since vaccination. has gone.

In any case, the primary immune protection by vaccines should be to recognize the virus soon after infection and destroy it before significant damage is caused.

“That’s why people get infected and why people don’t get seriously ill,” says Michelle C., an immunologist at Rockefeller University in New York. Nusenzweig said. “It’s almost inevitable, unless you’re going to give people boosters very often.”

There is limited evidence beyond anecdotal reports indicating whether breakthrough infections with the delta variant are more common or more likely to occur in other people. The CDC has recorded about 5,500 hospitalizations and deaths among vaccinated people, but this Not tracking mild breakthrough transitions.

Additional data is emerging from the COVID-19 Sports and Society Workgroup, a coalition of professional sports leagues working closely with CDC sports teams in the group, testing more than 10,000 people at least daily and all Sequencing the infections, Dr. Robbie Coin, a physician who worked with the Minnesota Timberwolves of the NBA.

He added that breakthrough transitions in the league appear to be more common with the delta version than with the alpha, previously identified in the UK. As would be expected, the vaccines significantly reduced the severity and duration of illness, with players returning less than two weeks after becoming infected, compared to about three weeks earlier in the pandemic.

But when they are infected, players carry a much higher amount of virus for seven to 10 days, while those infected with Alpha have two or three days, Dr Sikka said. He said infected players need to be quarantined, so the project hasn’t been able to track whether they spread the virus to others – but it’s likely they will.

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